Assay Detail

CHEMBL4723950

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Binding

Inhibition of rat small intestine GST using CDNB as substrate by spectrophotometric method

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Rattus norvegicus
Tissue	Small intestine
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Soluble Guanylate Cyclase Inhibitors Discovered among Natural Compounds.

Petrova ON,Lamarre I,Fasani F,Grillon C,Negrerie M
J Nat Prod (2020) 83 : 3642 -3651
PubMed 33290062 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	6.70	6.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL286494	HYPERICIN	3.0	1	6.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL286494	HYPERICIN	Ki	=	200.0	nM	6.70