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Assay Detail

CHEMBL4725116

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Functional
Antimigratory activity against mouse Natural killer cells assessed as inhibition of cell migration towards S1P by chemotaxis assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Natural killer cell
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Novel Potent Selective Orally Active S1P5 Receptor Antagonists.
Ma B,Guckian KM,Liu XG,Yang C,Li B,Scannevin R,Mingueneau M,Drouillard A,Walzer T
ACS Med Chem Lett (2021) 12 : 351 -355
PubMed 33738061 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.26 6.26

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4748198 1 6.26

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4748198 IC50 = 553.0 nM 6.26