Assay Detail
Binding
CHEMBL4725677
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PDE4D (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
3',5'-cyclic-AMP phosphodiesterase 4D (CHEMBL288) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Advances in the Development of Phosphodiesterase-4 Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.87 | 9.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3113734 | UK-500001 | 2.0 | 1 | 9.42 |
| CHEMBL4209111 | — | — | 1 | 8.10 |
| CHEMBL3585874 | — | — | 1 | 6.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3113734 | UK-500001 | IC50 | = | 0.38 | nM | 9.42 |
| CHEMBL4209111 | — | IC50 | = | 8.0 | nM | 8.10 |
| CHEMBL3585874 | — | IC50 | = | 800.0 | nM | 6.10 |