Assay Detail
Functional
CHEMBL4726181
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of goat anti-human IgM F(ab')-stimulated CD86 cell surface expression in human PBMC preincubated for 2 hrs followed by anti-human IgM stimulation for 18 hrs by flow cytometric analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PBMC |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of quinoline-based irreversible BTK inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 7.68 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4752700 | — | — | 1 | 7.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4752700 | — | EC50 | = | 21.0 | nM | 7.68 |