Assay Detail
Binding
CHEMBL4727002
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at mouse TRPV4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Transient receptor potential cation channel subfamily V member 4 (CHEMBL6126) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Modulation of TRPV4 and BKCa for treatment of brain diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.50 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2133556 | — | — | 1 | 7.77 |
| CHEMBL2324347 | — | — | 1 | 5.23 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2133556 | — | IC50 | = | 17.0 | nM | 7.77 |
| CHEMBL2324347 | — | IC50 | = | 5900.0 | nM | 5.23 |