Assay Detail
Binding
CHEMBL4729688
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human Cav2.2 expressed in HEK293 cells by whole cell patch clamp electrophysiology method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Voltage-dependent N-type calcium channel subunit alpha-1B (CHEMBL4478) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
The neuronal calcium ion channel activity of constrained analogues of MONIRO-1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.47 | 4.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4800369 | — | — | 1 | 4.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4800369 | — | IC50 | = | 34000.0 | nM | 4.47 |