Assay Detail
ADMET
CHEMBL4732475
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Cytotoxicity against human CHO-K1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Cricetulus griseus |
| Cell Type | CHO-K1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Benzimidazole-1,2,3-triazole hybrid molecules: synthesis and study of their interaction with G-quadruplex DNA
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 4.19 | 4.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4764858 | — | — | 1 | 4.25 |
| CHEMBL4781867 | — | — | 1 | 4.21 |
| CHEMBL65606 | TMPYP4 | — | 1 | 4.21 |
| CHEMBL4786759 | — | — | 1 | 4.20 |
| CHEMBL4750911 | — | — | 1 | 4.07 |
| CHEMBL4759761 | — | — | 1 | - |
| CHEMBL4753593 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4764858 | — | IC50 | = | 56100.0 | nM | 4.25 |
| CHEMBL4781867 | — | IC50 | = | 62210.0 | nM | 4.21 |
| CHEMBL65606 | TMPYP4 | IC50 | = | 61400.0 | nM | 4.21 |
| CHEMBL4786759 | — | IC50 | = | 62900.0 | nM | 4.20 |
| CHEMBL4750911 | — | IC50 | = | 85050.0 | nM | 4.07 |
| CHEMBL4759761 | — | IC50 | = | 100380.0 | nM | - |
| CHEMBL4753593 | — | IC50 | = | 114670.0 | nM | - |