Assay Detail
Binding
CHEMBL4732718
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Clostridium botulinum BoNT/A light chain
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Clostridium botulinum |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Botulinum neurotoxin type A (CHEMBL5192) ↗| Type | SINGLE PROTEIN |
| Organism | Clostridium botulinum |
Publication
Irreversible inhibition of BoNT/A protease: proximity-driven reactivity contingent upon a bifunctional approach
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.52 | 6.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL237370 | CINNAMIC ACID HYDROXAMATE | — | 1 | 6.52 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL237370 | CINNAMIC ACID HYDROXAMATE | Ki | = | 300.0 | nM | 6.52 |