Assay Detail
Binding
CHEMBL4732972
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of HIV1 protease
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human immunodeficiency virus 1 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Human immunodeficiency virus type 1 protease (CHEMBL243) ↗| Type | SINGLE PROTEIN |
| Organism | Human immunodeficiency virus 1 |
Publication
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.80 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL18389 | — | — | 1 | 6.80 |
| CHEMBL319408 | — | — | 1 | - |
| CHEMBL82338 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL18389 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL319408 | — | IC50 | < | 0.03 | nM | - |
| CHEMBL82338 | — | IC50 | >= | 3000.0 | nM | - |