Assay Detail
Binding
CHEMBL4732974
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Displacement of 125I-VCAM-Ig from VLA4 in human Jurkat cells incubated for 30 mins by scintillation counting method
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Cell Type | Jurkat |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 10.04 | 10.15 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4798264 | — | — | 1 | 10.15 |
| CHEMBL76119 | — | — | 1 | 10.10 |
| CHEMBL420936 | — | — | 1 | 10.00 |
| CHEMBL306827 | — | — | 1 | 9.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4798264 | — | IC50 | = | 0.07 | nM | 10.15 |
| CHEMBL76119 | — | IC50 | = | 0.08 | nM | 10.10 |
| CHEMBL420936 | — | IC50 | = | 0.1 | nM | 10.00 |
| CHEMBL306827 | — | IC50 | = | 0.13 | nM | 9.89 |