Assay Detail
Binding
CHEMBL4732995
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of [125]BH-CCK8 binding to guinea pig pancreas CCKAR by radioligand binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Cavia porcellus |
| Tissue | Pancreas |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.71 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4791620 | — | — | 1 | 5.80 |
| CHEMBL64605 | — | — | 1 | 5.75 |
| CHEMBL4784305 | — | — | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4791620 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL64605 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL4784305 | — | IC50 | = | 2700.0 | nM | 5.57 |