Assay Detail
ADMET
CHEMBL4733262
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against PHA-activated human peripheral blood lymphocytes assessed as cell viability after 72 hrs by luminescent assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | Lymphocyte |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Cyclic bridged analogs of isoCA-4: Design, synthesis and biological evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.66 | 8.37 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL498271 | — | — | 1 | 8.37 |
| CHEMBL4798567 | — | — | 1 | 6.94 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL498271 | — | IC50 | = | 4.3 | nM | 8.37 |
| CHEMBL4798567 | — | IC50 | = | 114.0 | nM | 6.94 |