Assay Detail
Binding
CHEMBL4734646
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of IDO1 in human HeLa cells preincubated for 1 hr followed by IFN-gamma stimulation and measured after 20 hrs by Ehrlich colorimetric reagent based assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of Indoleamine 2,3-Dioxygenase 1 Inhibitors for Cancer Therapy and Beyond: A Recent Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.84 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4161733 | — | — | 1 | 9.30 |
| CHEMBL4777480 | — | — | 1 | 8.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4161733 | — | IC50 | = | 0.5 | nM | 9.30 |
| CHEMBL4777480 | — | IC50 | = | 4.2 | nM | 8.38 |