Assay Detail
Binding
CHEMBL4734676
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Inhibition of IDO1 in human HeLa cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Development of Indoleamine 2,3-Dioxygenase 1 Inhibitors for Cancer Therapy and Beyond: A Recent Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.85 | 4.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4740878 | — | — | 1 | 4.95 |
| CHEMBL504816 | (L)-1-METHYLTRYPTOPHAN | — | 1 | 4.74 |
| CHEMBL571209 | INDOXIMOD | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4740878 | — | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL504816 | (L)-1-METHYLTRYPTOPHAN | IC50 | = | 18400.0 | nM | 4.74 |
| CHEMBL571209 | INDOXIMOD | IC50 | > | 2500000.0 | nM | - |