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Assay Detail

CHEMBL4734681

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of IDO1 in IFN-gamma stimulated human HeLa cells incubated for 6 hrs by p-dimethylaminobenzaldehyde reagent based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HeLa
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Indoleamine 2,3-dioxygenase 1 (CHEMBL4685)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Development of Indoleamine 2,3-Dioxygenase 1 Inhibitors for Cancer Therapy and Beyond: A Recent Perspective.
Feng X,Liao D,Liu D,Ping A,Li Z,Bian J
J Med Chem (2020) 63 : 15115 -15139
PubMed 33215494 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.37 5.37

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4579018 1 5.37

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4579018 IC50 = 4300.0 nM 5.37