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Assay Detail

CHEMBL4735356

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Functional
Antiproliferative activity against human Pfeiffer cells incubated for 10 days by cellTiter-glo luminesence method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type Pfeiffer
Confidence 1 — Organism
Curated By Autocuration

Target

Pfeiffer (CHEMBL4296489)
Type CELL-LINE
Organism Homo sapiens

Publication

Small Molecule Approaches for Targeting the Polycomb Repressive Complex 2 (PRC2) in Cancer.
Martin MC,Zeng G,Yu J,Schiltz GE
J Med Chem (2020) 63 : 15344 -15370
PubMed 33283516 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4104741 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4104741 IC50 = 69.0 nM 7.16