Assay Detail
Functional
CHEMBL4735514
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Antiproliferative activity against human MeWo cells assessed as reduction in cell viability measured after 96 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MeWo |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Imidazo[1,2-a]quinoxalines for melanoma treatment with original mechanism of action.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.32 | 8.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4781226 | — | — | 1 | 8.52 |
| CHEMBL557421 | — | — | 1 | 6.90 |
| CHEMBL3415553 | — | — | 1 | 6.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4781226 | — | IC50 | = | 3.0 | nM | 8.52 |
| CHEMBL557421 | — | IC50 | = | 125.0 | nM | 6.90 |
| CHEMBL3415553 | — | IC50 | = | 283.0 | nM | 6.55 |