Assay Detail
Functional
CHEMBL4738156
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human COLO 678 cells measured after 72 hrs by sulforhodamine B assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | COLO-678 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.68 | 4.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4760646 | — | — | 1 | 4.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4760646 | — | IC50 | = | 20730.0 | nM | 4.68 |