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Assay Detail

CHEMBL4738167

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Functional
Antiproliferative activity against human MINO cells measured after 72 hrs by CCK-8 assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MINO
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Discovery of novel ceramide analogs with favorable pharmacokinetic properties and combination with AKT inhibitor against colon cancer.
Gao F,Chen X,Lu J,Hu S,Xu H,Shi Y,Feng M,Ding J,Liu H,Luo C,Xie Z,Wang J
Eur J Med Chem (2021) 215 : 113274 -113274
PubMed 33592537 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.88 4.88

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4760646 1 4.88

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4760646 IC50 = 13330.0 nM 4.88