Assay Detail
Binding
CHEMBL4738693
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SARS CoV 3C-like protease expressed in Escherichia coli GJ1158 using 2-aminobenzoyl-SVTLQSG-Tyr(NO2)-R as substrate by FRET assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome-related coronavirus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Protease targeted COVID-19 drug discovery: What we have learned from the past SARS-CoV inhibitors?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.84 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL468553 | — | — | 1 | 6.30 |
| CHEMBL1339340 | — | — | 1 | 5.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL468553 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL1339340 | — | IC50 | = | 4300.0 | nM | 5.37 |