Assay Detail
Binding
CHEMBL4739783
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Inhibition of CDK2 (unknown origin)
37
Total Activities
37
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of cyclin-dependent kinases
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 37 | 7.10 | 8.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4756353 | — | — | 1 | 8.11 |
| CHEMBL4788136 | — | — | 1 | 8.01 |
| CHEMBL4641226 | — | — | 1 | 7.97 |
| CHEMBL4644893 | — | — | 1 | 7.96 |
| CHEMBL4777844 | — | — | 1 | 7.94 |
| CHEMBL4758168 | — | — | 1 | 7.92 |
| CHEMBL4753350 | — | — | 1 | 7.64 |
| CHEMBL4753717 | — | — | 1 | 7.63 |
| CHEMBL4786429 | — | — | 1 | 7.54 |
| CHEMBL4643057 | — | — | 1 | 7.23 |
| CHEMBL4761001 | — | — | 1 | 7.04 |
| CHEMBL4781539 | — | — | 1 | 6.97 |
| CHEMBL4744627 | — | — | 1 | 6.91 |
| CHEMBL4746993 | — | — | 1 | 6.90 |
| CHEMBL4761637 | — | — | 1 | 6.79 |
| CHEMBL4776271 | — | — | 1 | 6.76 |
| CHEMBL4793573 | — | — | 1 | 6.73 |
| CHEMBL4752238 | — | — | 1 | 6.60 |
| CHEMBL4756935 | — | — | 1 | 6.58 |
| CHEMBL4752989 | — | — | 1 | 6.54 |
| CHEMBL4797409 | — | — | 1 | 6.51 |
| CHEMBL4788401 | — | — | 1 | 6.48 |
| CHEMBL4744850 | — | — | 1 | 6.16 |
| CHEMBL4781334 | — | — | 1 | 5.50 |
| CHEMBL4764719 | — | — | 1 | - |
| CHEMBL4794338 | — | — | 1 | - |
| CHEMBL4763202 | — | — | 1 | - |
| CHEMBL4797288 | — | — | 1 | - |
| CHEMBL4643754 | — | — | 1 | - |
| CHEMBL4777761 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4756353 | — | IC50 | = | 7.8 | nM | 8.11 |
| CHEMBL4788136 | — | IC50 | = | 9.86 | nM | 8.01 |
| CHEMBL4641226 | — | IC50 | = | 10.8 | nM | 7.97 |
| CHEMBL4644893 | — | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL4777844 | — | IC50 | = | 11.5 | nM | 7.94 |
| CHEMBL4758168 | — | IC50 | = | 11.9 | nM | 7.92 |
| CHEMBL4753350 | — | IC50 | = | 22.9 | nM | 7.64 |
| CHEMBL4753717 | — | IC50 | = | 23.3 | nM | 7.63 |
| CHEMBL4786429 | — | IC50 | = | 29.0 | nM | 7.54 |
| CHEMBL4643057 | — | IC50 | = | 58.8 | nM | 7.23 |
| CHEMBL4761001 | — | IC50 | = | 92.3 | nM | 7.04 |
| CHEMBL4781539 | — | IC50 | = | 108.0 | nM | 6.97 |
| CHEMBL4744627 | — | IC50 | = | 124.0 | nM | 6.91 |
| CHEMBL4746993 | — | IC50 | = | 126.0 | nM | 6.90 |
| CHEMBL4761637 | — | IC50 | = | 162.0 | nM | 6.79 |
| CHEMBL4776271 | — | IC50 | = | 174.0 | nM | 6.76 |
| CHEMBL4793573 | — | IC50 | = | 185.0 | nM | 6.73 |
| CHEMBL4752238 | — | IC50 | = | 251.0 | nM | 6.60 |
| CHEMBL4756935 | — | IC50 | = | 264.0 | nM | 6.58 |
| CHEMBL4752989 | — | IC50 | = | 286.0 | nM | 6.54 |
| CHEMBL4797409 | — | IC50 | = | 312.0 | nM | 6.51 |
| CHEMBL4788401 | — | IC50 | = | 334.0 | nM | 6.48 |
| CHEMBL4744850 | — | IC50 | = | 689.0 | nM | 6.16 |
| CHEMBL4781334 | — | IC50 | = | 3170.0 | nM | 5.50 |
| CHEMBL4790868 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4749580 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4763994 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4786324 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4789890 | — | IC50 | > | 370.0 | nM | - |
| CHEMBL4789917 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4743840 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4777761 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4643754 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4797288 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4763202 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4794338 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL4764719 | — | IC50 | > | 1000.0 | nM | - |