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Assay Detail

CHEMBL4739786

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Functional
Antiproliferative activity against human HAP1 cells measured after 72 hrs by CellTiter-Glo Luminescent Cell Viability Assay
15
Total Activities
15
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type HAP1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Inhibitors of cyclin-dependent kinases
(2020)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 15 6.88 8.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4781539 1 8.10
CHEMBL4777841 1 7.21
CHEMBL4788401 1 6.92
CHEMBL4756935 1 6.71
CHEMBL4751989 1 6.38
CHEMBL4636175 1 5.93
CHEMBL4777761 1 -
CHEMBL4790868 1 -
CHEMBL4749580 1 -
CHEMBL4763994 1 -
CHEMBL4743840 1 -
CHEMBL4763202 1 -
CHEMBL4794338 1 -
CHEMBL4764719 1 -
CHEMBL4781334 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4781539 IC50 = 8.0 nM 8.10
CHEMBL4777841 IC50 = 61.0 nM 7.21
CHEMBL4788401 IC50 = 119.0 nM 6.92
CHEMBL4756935 IC50 = 197.0 nM 6.71
CHEMBL4751989 IC50 = 412.0 nM 6.38
CHEMBL4636175 IC50 = 1180.0 nM 5.93
CHEMBL4777761 IC50 > 10000.0 nM -
CHEMBL4790868 IC50 > 10000.0 nM -
CHEMBL4749580 IC50 > 10000.0 nM -
CHEMBL4763994 IC50 > 10000.0 nM -
CHEMBL4743840 IC50 > 10000.0 nM -
CHEMBL4763202 IC50 > 10000.0 nM -
CHEMBL4794338 IC50 > 10000.0 nM -
CHEMBL4764719 IC50 > 10000.0 nM -
CHEMBL4781334 IC50 > 10000.0 nM -