Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4739827

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Induction of chondrogenesis in human MSC assessed as incubated for 6 days by rhodamine B and Nile red staining based imaging analysis
ChEMBL ↗
286
Total Activities
286
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type BMMSC
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545) ↗
Type UNCHECKED

Publication

Methods of treating cartilage disorders through inhibition of clk and dyrk
(2020)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 286 7.43 8.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4777958 — — 1 8.64
CHEMBL4743122 — — 1 8.16
CHEMBL4749604 — — 1 8.00
CHEMBL4758045 — — 1 8.00
CHEMBL4754669 — — 1 8.00
CHEMBL4748599 — — 1 8.00
CHEMBL4749262 — — 1 8.00
CHEMBL4755388 — — 1 8.00
CHEMBL4742246 — — 1 8.00
CHEMBL4797672 — — 1 8.00
CHEMBL4786418 — — 1 8.00
CHEMBL4759166 — — 1 8.00
CHEMBL4761624 — — 1 8.00
CHEMBL4748882 — — 1 8.00
CHEMBL4793590 — — 1 8.00
CHEMBL4755713 — — 1 8.00
CHEMBL4763435 — — 1 8.00
CHEMBL4776672 — — 1 8.00
CHEMBL4753382 — — 1 8.00
CHEMBL4755429 — — 1 8.00
CHEMBL4786746 — — 1 8.00
CHEMBL4763852 — — 1 8.00
CHEMBL4752659 — — 1 8.00
CHEMBL4798488 — — 1 8.00
CHEMBL4755308 — — 1 8.00
CHEMBL4783783 — — 1 8.00
CHEMBL4746269 — — 1 8.00
CHEMBL4745586 — — 1 8.00
CHEMBL4762155 — — 1 8.00
CHEMBL4747048 — — 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4777958 — EC50 = 2.29 nM 8.64
CHEMBL4743122 — EC50 = 6.86 nM 8.16
CHEMBL4799685 — EC50 = 10.0 nM 8.00
CHEMBL4754964 — EC50 = 10.0 nM 8.00
CHEMBL4745435 — EC50 = 10.0 nM 8.00
CHEMBL4754308 — EC50 = 10.0 nM 8.00
CHEMBL4786950 — EC50 = 10.0 nM 8.00
CHEMBL4749604 — EC50 = 10.0 nM 8.00
CHEMBL4779327 — EC50 = 10.0 nM 8.00
CHEMBL4747048 — EC50 = 10.0 nM 8.00
CHEMBL4799281 — EC50 = 10.0 nM 8.00
CHEMBL4755078 — EC50 = 10.0 nM 8.00
CHEMBL4790211 — EC50 = 10.0 nM 8.00
CHEMBL4763405 — EC50 = 10.0 nM 8.00
CHEMBL4788785 — EC50 = 10.0 nM 8.00
CHEMBL4761965 — EC50 = 10.0 nM 8.00
CHEMBL4759161 — EC50 = 10.0 nM 8.00
CHEMBL4780582 — EC50 = 10.0 nM 8.00
CHEMBL4778742 — EC50 = 10.0 nM 8.00
CHEMBL4753703 — EC50 = 10.0 nM 8.00
CHEMBL4778624 — EC50 = 10.0 nM 8.00
CHEMBL4757198 — EC50 = 10.0 nM 8.00
CHEMBL4741420 — EC50 = 10.0 nM 8.00
CHEMBL4742246 — EC50 = 10.0 nM 8.00
CHEMBL4756072 — EC50 = 10.0 nM 8.00
CHEMBL4762727 — EC50 = 10.0 nM 8.00
CHEMBL4759361 — EC50 = 10.0 nM 8.00
CHEMBL4741533 — EC50 = 10.0 nM 8.00
CHEMBL4755429 — EC50 = 10.0 nM 8.00
CHEMBL4740858 — EC50 = 10.0 nM 8.00
CHEMBL4753382 — EC50 = 10.0 nM 8.00
CHEMBL4776672 — EC50 = 10.0 nM 8.00
CHEMBL4797292 — EC50 = 10.0 nM 8.00
CHEMBL4746032 — EC50 = 10.0 nM 8.00
CHEMBL4763435 — EC50 = 10.0 nM 8.00
CHEMBL4757131 — EC50 = 10.0 nM 8.00
CHEMBL4755713 — EC50 = 10.0 nM 8.00
CHEMBL4793590 — EC50 = 10.0 nM 8.00
CHEMBL4758482 — EC50 = 10.0 nM 8.00
CHEMBL4747611 — EC50 = 10.0 nM 8.00
CHEMBL4748882 — EC50 = 10.0 nM 8.00
CHEMBL4759093 — EC50 = 10.0 nM 8.00
CHEMBL4788538 — EC50 = 10.0 nM 8.00
CHEMBL4761624 — EC50 = 10.0 nM 8.00
CHEMBL4782038 — EC50 = 10.0 nM 8.00
CHEMBL4759166 — EC50 = 10.0 nM 8.00
CHEMBL4792964 — EC50 = 10.0 nM 8.00
CHEMBL4763601 — EC50 = 10.0 nM 8.00
CHEMBL4786418 — EC50 = 10.0 nM 8.00
CHEMBL4750750 — EC50 = 10.0 nM 8.00