Assay Detail
Functional
CHEMBL4742478
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Inhibition of colony formation of human SW-620 cells incubated for 11 days (Every 3 days medium is changed by fresh medium and compounds were added freshly) by crystal violet staining based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW-620 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Condensed tricyclic compounds as protein kinase inhibitors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.08 | 7.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4791276 | — | — | 1 | 7.29 |
| CHEMBL4777501 | — | — | 1 | 5.68 |
| CHEMBL4776585 | — | — | 1 | 5.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4791276 | — | EC50 | = | 51.0 | nM | 7.29 |
| CHEMBL4777501 | — | EC50 | = | 2110.0 | nM | 5.68 |
| CHEMBL4776585 | — | EC50 | = | 5430.0 | nM | 5.26 |