Assay Detail
Binding
CHEMBL4742483
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CDK7/Cyclin H/MAT1 (unknown origin) using 5-FAM-CDK7tide peptide substrate incubated for 35 mins
277
Total Activities
277
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Inhibitors of cyclin-dependent kinase 7 (cdk7)
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 277 | 7.50 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4777419 | — | — | 1 | 7.70 |
| CHEMBL4792193 | — | — | 1 | 7.70 |
| CHEMBL4797783 | — | — | 1 | 7.70 |
| CHEMBL4791262 | — | — | 1 | 7.70 |
| CHEMBL4777758 | — | — | 1 | 7.70 |
| CHEMBL4788043 | — | — | 1 | 7.70 |
| CHEMBL4785708 | — | — | 1 | 7.70 |
| CHEMBL4781205 | — | — | 1 | 7.70 |
| CHEMBL4793626 | — | — | 1 | 7.70 |
| CHEMBL4786870 | — | — | 1 | 7.70 |
| CHEMBL4781209 | — | — | 1 | 7.70 |
| CHEMBL4790299 | — | — | 1 | 7.70 |
| CHEMBL4790200 | — | — | 1 | 7.70 |
| CHEMBL4792063 | — | — | 1 | 7.70 |
| CHEMBL4783735 | — | — | 1 | 7.70 |
| CHEMBL4797244 | — | — | 1 | 7.70 |
| CHEMBL4787747 | — | — | 1 | 7.70 |
| CHEMBL4796480 | — | — | 1 | 7.70 |
| CHEMBL4785609 | — | — | 1 | 7.70 |
| CHEMBL4779588 | — | — | 1 | 7.70 |
| CHEMBL4786864 | — | — | 1 | 7.70 |
| CHEMBL4790718 | — | — | 1 | 7.70 |
| CHEMBL4792679 | — | — | 1 | 7.70 |
| CHEMBL4796032 | — | — | 1 | 7.70 |
| CHEMBL4777842 | — | — | 1 | 7.70 |
| CHEMBL4793244 | — | — | 1 | 7.70 |
| CHEMBL4788933 | — | — | 1 | 7.70 |
| CHEMBL4781069 | — | — | 1 | 7.70 |
| CHEMBL4783125 | — | — | 1 | 7.70 |
| CHEMBL4800180 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4778051 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4792632 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4796907 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4789342 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4797260 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4792784 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4779834 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4781253 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4799169 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4800597 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4790437 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4796263 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4788987 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4779846 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4777468 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4786413 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4796697 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4784288 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4798073 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4795466 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4790773 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4790770 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4784046 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4796874 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4797856 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4787197 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4785708 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4784604 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4789131 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4788043 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4791262 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4780112 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4787811 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4780460 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4795042 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4797783 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4782858 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4795015 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4781758 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4795275 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4791765 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4795301 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4792193 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4778657 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4792958 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4783754 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4791188 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4786193 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4783627 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4785594 | — | IC50 | = | 20.0 | nM | 7.70 |