Assay Detail
Functional
CHEMBL4742487
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of cell proliferation of human A673 cells incubated for 72 hrs by CyQUANT assay
277
Total Activities
277
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A673 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibitors of cyclin-dependent kinase 7 (cdk7)
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 277 | 7.29 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4778981 | — | — | 1 | 7.70 |
| CHEMBL4783460 | — | — | 1 | 7.70 |
| CHEMBL4796907 | — | — | 1 | 7.70 |
| CHEMBL4797720 | — | — | 1 | 7.70 |
| CHEMBL4786193 | — | — | 1 | 7.70 |
| CHEMBL4797765 | — | — | 1 | 7.70 |
| CHEMBL4778994 | — | — | 1 | 7.70 |
| CHEMBL4777758 | — | — | 1 | 7.70 |
| CHEMBL4794715 | — | — | 1 | 7.70 |
| CHEMBL4795935 | — | — | 1 | 7.70 |
| CHEMBL4786870 | — | — | 1 | 7.70 |
| CHEMBL4781209 | — | — | 1 | 7.70 |
| CHEMBL4790299 | — | — | 1 | 7.70 |
| CHEMBL4795693 | — | — | 1 | 7.70 |
| CHEMBL4792813 | — | — | 1 | 7.70 |
| CHEMBL4533453 | — | — | 1 | 7.70 |
| CHEMBL4799405 | — | — | 1 | 7.70 |
| CHEMBL4787747 | — | — | 1 | 7.70 |
| CHEMBL4786864 | — | — | 1 | 7.70 |
| CHEMBL4790718 | — | — | 1 | 7.70 |
| CHEMBL4796559 | — | — | 1 | 7.70 |
| CHEMBL4792679 | — | — | 1 | 7.70 |
| CHEMBL4796032 | — | — | 1 | 7.70 |
| CHEMBL4794403 | — | — | 1 | 7.70 |
| CHEMBL4793244 | — | — | 1 | 7.70 |
| CHEMBL4800535 | — | — | 1 | 7.70 |
| CHEMBL4783125 | — | — | 1 | 7.70 |
| CHEMBL4800180 | — | — | 1 | 7.70 |
| CHEMBL4797244 | — | — | 1 | 7.70 |
| CHEMBL4474655 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4795693 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4784288 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4786413 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4777468 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4794715 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4789351 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4798558 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4784042 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4798916 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4795935 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4786870 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4781209 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4790299 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4782690 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4781253 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4792813 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4792848 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4800597 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4786864 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4800535 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4533453 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4788795 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4790249 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4793244 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4799169 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4797694 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4793351 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4783758 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4799586 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4780149 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4795059 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4783460 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4796907 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4797720 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4778825 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4783495 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4786193 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4799114 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4776523 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4778885 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4793690 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4797765 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4780924 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4788873 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4782475 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4790773 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4796874 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4778994 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4794831 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL4777758 | — | IC50 | = | 20.0 | nM | 7.70 |