Assay Detail
Binding
CHEMBL4765715
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Inhibition of TrkC (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Indole-like Trk receptor antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 8.15 | 8.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL104333 | — | — | 1 | 8.39 |
| CHEMBL104519 | — | — | 1 | 8.37 |
| CHEMBL104279 | — | — | 1 | 8.16 |
| CHEMBL106226 | — | — | 1 | 8.05 |
| CHEMBL4798255 | — | — | 1 | 8.01 |
| CHEMBL322153 | — | — | 1 | 7.93 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL104333 | — | IC50 | = | 4.1 | nM | 8.39 |
| CHEMBL104519 | — | IC50 | = | 4.25 | nM | 8.37 |
| CHEMBL104279 | — | IC50 | = | 6.86 | nM | 8.16 |
| CHEMBL106226 | — | IC50 | = | 8.82 | nM | 8.05 |
| CHEMBL4798255 | — | IC50 | = | 9.72 | nM | 8.01 |
| CHEMBL322153 | — | IC50 | = | 11.67 | nM | 7.93 |