Assay Detail
Binding
CHEMBL4767689
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of TrxR in rat liver assessed as reduction in TNB formation using DTNB and NADPH as substrate preincubated with enzyme for 15 mins followed by NADPH addition by absorbance based analysis
4
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Efficient identification of novel anti-glioma lead compounds by machine learning models.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.60 | 4.60 |
| Inhibition | 2 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4100154 | — | — | 2 | 4.60 |
| CHEMBL4061960 | — | — | 2 | 4.60 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4100154 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL4061960 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL4100154 | — | Inhibition | - | % | - | |
| CHEMBL4061960 | — | Inhibition | - | % | - |