Assay Detail
Functional
CHEMBL4772222
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Agonist activity at human NPFFR2 expressed in CHO cells assessed as inhibition of forskolin-induced intracellular cyclic cAMP accumulation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 7.10 | 8.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL429731 | — | — | 1 | 8.50 |
| CHEMBL326770 | — | — | 1 | 6.51 |
| CHEMBL262202 | — | — | 1 | 6.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL429731 | — | EC50 | = | 3.16 | nM | 8.50 |
| CHEMBL326770 | — | EC50 | = | 309.0 | nM | 6.51 |
| CHEMBL262202 | — | EC50 | = | 517.0 | nM | 6.29 |