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Assay Detail

CHEMBL4772278

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of 125I-NPFF from human NPFFR2 incubated for 2 hrs by TopCount scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Neuropeptide FF receptor 2 (CHEMBL5952)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development.
Nguyen T,Marusich J,Li JX,Zhang Y
J Med Chem (2020) 63 : 12387 -12402
PubMed 32673481 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.90 6.90

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4784123 1 6.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4784123 Ki = 125.89 nM 6.90