Assay Detail
Binding
CHEMBL4773799
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of SARS CoV2 C-terminal His-tagged 3CL protease expressed in Escherichia coli BL21 DE3 using Mca-AVLQSGFR-K(Dnp)K as substrate by fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome coronavirus 2 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Potent inhibitors of SARS-CoV-2 3C-like protease derived from N-substituted isatin compounds.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.81 | 5.81 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3545157 | TIDEGLUSIB | 2.0 | 1 | 5.81 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3545157 | TIDEGLUSIB | IC50 | = | 1550.0 | nM | 5.81 |