Assay Detail
Functional
CHEMBL4774401
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Antiproliferative activity against human Bel-7402 cells assessed as reduction in cell viability incubated for 48 hrs by xCELLigence RTCA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Bel-7402 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and anti-cancer activity of pyrrole-imidazole polyamides through target-downregulation of c-kit gene expression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.68 | 4.95 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4793572 | — | — | 1 | 4.95 |
| CHEMBL4790012 | — | — | 1 | 4.83 |
| CHEMBL1642 | IMATINIB MESYLATE | 4.0 | 1 | 4.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4793572 | — | IC50 | = | 11190.0 | nM | 4.95 |
| CHEMBL4790012 | — | IC50 | = | 14870.0 | nM | 4.83 |
| CHEMBL1642 | IMATINIB MESYLATE | IC50 | = | 55520.0 | nM | 4.26 |