Assay Detail
Functional
CHEMBL4774403
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Antiproliferative activity against human SGC7901 cells assessed as reduction in cell viability incubated for 48 hrs by xCELLigence RTCA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SGC-7901 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis and anti-cancer activity of pyrrole-imidazole polyamides through target-downregulation of c-kit gene expression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.81 | 6.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1642 | IMATINIB MESYLATE | 4.0 | 1 | 6.68 |
| CHEMBL4793572 | — | — | 1 | 5.53 |
| CHEMBL4790012 | — | — | 1 | 5.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1642 | IMATINIB MESYLATE | IC50 | = | 208.0 | nM | 6.68 |
| CHEMBL4793572 | — | IC50 | = | 2960.0 | nM | 5.53 |
| CHEMBL4790012 | — | IC50 | = | 6050.0 | nM | 5.22 |