Assay Detail
Binding
CHEMBL4775083
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of mitochondrial complex 1 in human PC-3 cell mitochondria assessed as reduction in oxygen consumption using glutamate/malate/ADP as substrate by oxygen sensitive fluorescent dye based assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Subcellular | Mitochondria |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Why All the Fuss about Oxidative Phosphorylation (OXPHOS)?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 8.00 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4303384 | — | — | 1 | 8.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4303384 | — | IC50 | = | 10.0 | nM | 8.00 |