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Assay Detail

CHEMBL4775149

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human CDK7 incubated for 180 mins by LanthaScreen Eu Kinase binding assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 7 (CHEMBL3055)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthetic Lethality through the Lens of Medicinal Chemistry.
Myers SH,Ortega JA,Cavalli A
J Med Chem (2020) 63 : 14151 -14183
PubMed 33135887 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.49 8.49

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3603847 1 8.49

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3603847 IC50 = 3.2 nM 8.49