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Assay Detail

CHEMBL4775162

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human RAD51 using 90-mer ssDNA as substrate measured after 30 mins by D-loop assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

DNA repair protein RAD51 homolog 1 (CHEMBL2034807)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Synthetic Lethality through the Lens of Medicinal Chemistry.
Myers SH,Ortega JA,Cavalli A
J Med Chem (2020) 63 : 14151 -14183
PubMed 33135887 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.56 4.56

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1567670 1 4.56

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1567670 IC50 = 27400.0 nM 4.56