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Assay Detail

CHEMBL4775328

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Mycobacterium tuberculosis thymidylate kinase
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Mycobacterium tuberculosis
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

2-((3,5-Dinitrobenzyl)thio)quinazolinones: Potent Antimycobacterial Agents Activated by Deazaflavin (F)-Dependent Nitroreductase (Ddn).
Jian Y,Forbes HE,Hulpia F,Risseeuw MDP,Caljon G,Munier-Lehmann H,Boshoff HIM,Van Calenbergh S
J Med Chem (2021) 64 : 440 -457
PubMed 33347317 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.82 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3394148 1 5.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3394148 IC50 = 1500.0 nM 5.82