Assay Detail
Binding
CHEMBL4775437
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Binding affinity to human integrin alphaVbeta6 incubated for 1 hr by ELISA based solid phase integrin binding assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 6 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Tuning the Biological Activity of RGD Peptides with Halotryptophans†.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.60 | 9.59 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4780301 | — | — | 1 | 9.59 |
| CHEMBL4795994 | — | — | 1 | 7.50 |
| CHEMBL4790959 | — | — | 1 | 7.44 |
| CHEMBL4793182 | — | — | 1 | 7.30 |
| CHEMBL4787559 | — | — | 1 | 7.27 |
| CHEMBL4787900 | — | — | 1 | 6.52 |
| CHEMBL916 | TIROFIBAN | 4.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4780301 | — | IC50 | = | 0.26 | nM | 9.59 |
| CHEMBL4795994 | — | IC50 | = | 32.0 | nM | 7.50 |
| CHEMBL4790959 | — | IC50 | = | 36.0 | nM | 7.44 |
| CHEMBL4793182 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL4787559 | — | IC50 | = | 54.0 | nM | 7.27 |
| CHEMBL4787900 | — | IC50 | = | 299.0 | nM | 6.52 |
| CHEMBL916 | TIROFIBAN | IC50 | - | — | - |