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Assay Detail

CHEMBL4775596

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of serum-induced cell migration of human MDA-MB-231 cells incubated for 16 hrs by Boyden chamber assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Sialyltransferase Inhibitors Suppress Breast Cancer Metastasis.
Fu CW,Tsai HE,Chen WS,Chang TT,Chen CL,Hsiao PW,Li WS
J Med Chem (2021) 64 : 527 -542
PubMed 33371679 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.95 4.97

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4780118 1 4.97
CHEMBL4785375 1 4.92

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4780118 IC50 = 10640.0 nM 4.97
CHEMBL4785375 IC50 = 12000.0 nM 4.92