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Assay Detail

CHEMBL4807552

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Potentiation of paclitaxel-induced cytotoxicity against human PEO1 cells assessed as paclitaxel IC50 at 44 uM after 72 hrs by ATPlite assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type PEO1
Confidence 1 — Organism
Curated By Autocuration

Target

PEO1 (CHEMBL4296485)
Type CELL-LINE
Organism Homo sapiens

Publication

Nek6 kinase inhibitors useful for the treatment of solid tumors
(2019)

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.19 6.19

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4875865 1 6.19

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4875865 IC50 = 640.0 nM 6.19