Assay Detail
Binding
CHEMBL4807553
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of NEK6 (unknown origin) using ULight-p70 S6K peptide as substrate incubated for 90 mins by LANCE Ultra kinase assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase Nek6 (CHEMBL4309) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Nek6 kinase inhibitors useful for the treatment of solid tumors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.53 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4862849 | — | — | 1 | 5.58 |
| CHEMBL4875865 | — | — | 1 | 5.47 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4862849 | — | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL4875865 | — | IC50 | = | 3400.0 | nM | 5.47 |