Assay Detail
Binding
CHEMBL4808782
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of pig brain tubulin polymerization by spectrophotometric method
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Tissue | Brain |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Discovery of Novel Benzimidazole and Indazole Analogues as Tubulin Polymerization Inhibitors with Potent Anticancer Activities.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.37 | 5.60 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4852240 | — | — | 2 | 5.60 |
| CHEMBL107 | COLCHICINE | 4.0 | 1 | 5.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4852240 | — | IC50 | = | 2520.0 | nM | 5.60 |
| CHEMBL107 | COLCHICINE | IC50 | = | 7300.0 | nM | 5.14 |
| CHEMBL4852240 | — | Inhibition | - | % | - |