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Assay Detail

CHEMBL4810323

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to SARS coronavirus 1 3CL protease using Dabcyl-KTSAVLQ/SGFRKME-Edans as substrate measured by FRET assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Severe acute respiratory syndrome-related coronavirus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors.
Vankadara S, Wong YX, Liu B, See YY, Tan LH, Tan QW, Wang G, Karuna R, Guo X, Tan ST, Fong JY, Joy J, Chia CSB.
Bioorg Med Chem Lett (2021) 48 : 128263 -128263
PubMed 34271072 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.28 7.28

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4852855 1 7.28

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4852855 Ki = 53.0 nM 7.28