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Assay Detail

CHEMBL4812652

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of GCPII (unknown origin) NAALADase activity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glutamate carboxypeptidase 2 (CHEMBL1892)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Dipeptide inhibitors of the prostate specific membrane antigen (PSMA): A comparison of urea and thiourea derivatives.
Young JD, Ma MT, Eykyn TR, Atkinson RA, Abbate V, Cilibrizzi A, Hider RC, Blower PJ.
Bioorg Med Chem Lett (2021) 42 : 128044 -128044
PubMed 33865971 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 9.52 9.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL189217 1 9.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL189217 Ki = 0.3 nM 9.52