Assay Detail
Functional
CHEMBL4812809
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Cytotoxicity against human MCF7 cells assessed as cell viability measured by MTT assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and biological evaluation of novel benzo[a]pyridazino[3,4-c]phenazine derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 4.66 | 5.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | — | 1 | 5.61 |
| CHEMBL4876801 | — | — | 1 | 4.66 |
| CHEMBL4874311 | — | — | 1 | 4.66 |
| CHEMBL4863877 | — | — | 1 | 4.20 |
| CHEMBL4848398 | — | — | 1 | 4.15 |
| CHEMBL4867599 | — | — | 1 | - |
| CHEMBL4856244 | — | — | 1 | - |
| CHEMBL4870249 | — | — | 1 | - |
| CHEMBL4864553 | — | — | 1 | - |
| CHEMBL4862092 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL123 | ELLIPTECINE | IC50 | = | 2480.0 | nM | 5.61 |
| CHEMBL4876801 | — | IC50 | = | 22040.0 | nM | 4.66 |
| CHEMBL4874311 | — | IC50 | = | 21830.0 | nM | 4.66 |
| CHEMBL4863877 | — | IC50 | = | 62740.0 | nM | 4.20 |
| CHEMBL4848398 | — | IC50 | = | 70660.0 | nM | 4.15 |
| CHEMBL4867599 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4856244 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4870249 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4864553 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4862092 | — | IC50 | > | 100000.0 | nM | - |