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Assay Detail

CHEMBL4812978

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human BALL-1 cells assessed as reduction in cell viability incubated for 24 hrs by WST-8 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type BALL-1
Confidence 1 — Organism
Curated By Autocuration

Target

BALL-1 (CHEMBL2366269)
Type CELL-LINE
Organism Homo sapiens

Publication

Epo-C12 inhibits peroxiredoxin 1 peroxidase activity.
Yoda T, Furuta M, Tsutsumi T, Ikeda S, Yukizawa S, Arai S, Morita A, Yamatoya K, Nakata K, Tomoshige S, Ohgane K, Furuyama Y, Sakaguchi K, Sugawara F, Kobayashi S, Ikekita M, Kuramochi K.
Bioorg Med Chem (2021) 41 : 116203 -116203
PubMed 34015702 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.67 5.98

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4860684 1 5.98
CHEMBL478290 1 5.36

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4860684 IC50 = 1050.0 nM 5.98
CHEMBL478290 IC50 = 4410.0 nM 5.36