Assay Detail
Binding
CHEMBL4813156
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]BNZA from Nav1.5 (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Sodium channel protein type 5 subunit alpha (CHEMBL1980) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Identification of aryl sulfonamides as novel and potent inhibitors of Na<sub>V</sub>1.5.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.07 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4854735 | — | — | 1 | 6.43 |
| CHEMBL4849813 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4854735 | — | Ki | = | 370.0 | nM | 6.43 |
| CHEMBL4849813 | — | Ki | = | 2020.0 | nM | 5.70 |