Assay Detail
Binding
CHEMBL4814399
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant mouse LSD2 expressed in Escherichia coli using histone H3 peptide dimethylated at Lys4 as substrate by peroxidase-coupled assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Lysine-specific histone demethylase 1B (CHEMBL4879491) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Tranylcypromine Based Lysine-Specific Demethylase 1 Inhibitor: Summary and Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.44 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4871159 | — | — | 1 | 4.70 |
| CHEMBL3104337 | — | — | 1 | 4.42 |
| CHEMBL3416425 | — | — | 1 | 4.21 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4871159 | — | Ki | = | 20000.0 | nM | 4.70 |
| CHEMBL3104337 | — | Ki | = | 38000.0 | nM | 4.42 |
| CHEMBL3416425 | — | Ki | = | 61000.0 | nM | 4.21 |