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Assay Detail

CHEMBL4814401

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant human MAO-B expressed in Pichia pastoris using benzylamine as substrate by peroxidase-coupled method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Amine oxidase [flavin-containing] B (CHEMBL2039)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Tranylcypromine Based Lysine-Specific Demethylase 1 Inhibitor: Summary and Perspective.
Dai XJ, Liu Y, Xiong XP, Xue LP, Zheng YC, Liu HM.
J Med Chem (2020) 63 : 14197 -14215
PubMed 32931269 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.30 5.46

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3416425 1 5.46
CHEMBL4871159 1 5.13

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3416425 Ki = 3500.0 nM 5.46
CHEMBL4871159 Ki = 7400.0 nM 5.13