Assay Detail
Binding
CHEMBL4814441
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human MAO-A expressed in baculovirus infected BTI insect cells by fluorescence method
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | BTI |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Tranylcypromine Based Lysine-Specific Demethylase 1 Inhibitor: Summary and Perspective.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.30 | 5.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4855475 | — | — | 1 | 5.60 |
| CHEMBL4872682 | — | — | 1 | 5.43 |
| CHEMBL4857247 | — | — | 1 | 5.30 |
| CHEMBL4861378 | — | — | 1 | 5.23 |
| CHEMBL4851339 | — | — | 1 | 4.93 |
| CHEMBL4856722 | — | — | 2 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4855475 | — | IC50 | = | 2500.0 | nM | 5.60 |
| CHEMBL4872682 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL4857247 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL4861378 | — | IC50 | = | 5900.0 | nM | 5.23 |
| CHEMBL4851339 | — | IC50 | = | 11700.0 | nM | 4.93 |
| CHEMBL4856722 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL4856722 | — | IC50 | > | 100000.0 | nM | - |